The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells

Rhabdomyosarcoma (RMS), the most common cancer of connective tissues in pediatrics, is often resistant to conventional therapies. One underlying mechanism of this resistance is the overexpression of Inhibitor of Apoptosis (IAP) proteins, leading to a dysfunctional cell death program within tumor cel...

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Publicat a:Front Immunol
Autors principals: Fischer, Kyra, Tognarelli, Sara, Roesler, Stefanie, Boedicker, Cathinka, Schubert, Ralf, Steinle, Alexander, Klingebiel, Thomas, Bader, Peter, Fulda, Simone, Ullrich, Evelyn
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339542/
https://ncbi.nlm.nih.gov/pubmed/28326081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00202
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