The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells

Rhabdomyosarcoma (RMS), the most common cancer of connective tissues in pediatrics, is often resistant to conventional therapies. One underlying mechanism of this resistance is the overexpression of Inhibitor of Apoptosis (IAP) proteins, leading to a dysfunctional cell death program within tumor cel...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Fischer, Kyra, Tognarelli, Sara, Roesler, Stefanie, Boedicker, Cathinka, Schubert, Ralf, Steinle, Alexander, Klingebiel, Thomas, Bader, Peter, Fulda, Simone, Ullrich, Evelyn
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339542/
https://ncbi.nlm.nih.gov/pubmed/28326081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00202
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