The SMAC mimetic BV6 induces cell death and sensitizes different cell lines to TNF-α and TRAIL-induced apoptosis

The inhibitors of apoptosis proteins are implicated in promoting cancer cells survival and resistance toward immune surveillance and chemotherapy. Second mitochondria-derived activator of caspases (SMAC) mimetics are novel compounds developed to mimic the inhibitory effect of the endogenous SMAC/DIA...

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Vydáno v:Exp Biol Med (Maywood)
Hlavní autoři: El-Mesery, Mohamed, Shaker, Mohamed E, Elgaml, Abdelaziz
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102137/
https://ncbi.nlm.nih.gov/pubmed/27465142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216661779
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