SMAC Mimetic BV6 Induces Cell Death in Monocytes and Maturation of Monocyte-Derived Dendritic Cells

BACKGROUND: Compounds mimicking the inhibitory effect of SMAC / DIABLO on X-linked inhibitor of apoptosis (XIAP) have been developed with the aim to achieve sensitization for apoptosis of tumor cells resistant due to deregulated XIAP expression. It turned out that SMAC mimetics also have complex eff...

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Hlavní autoři: Müller-Sienerth, Nicole, Dietz, Lena, Holtz, Philipp, Kapp, Markus, Grigoleit, Götz Ulrich, Schmuck, Carsten, Wajant, Harald, Siegmund, Daniela
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127953/
https://ncbi.nlm.nih.gov/pubmed/21738708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021556
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