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Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis
Macrophages express TNFR1 as well as TNFR2 and are also major producers of tumor necrosis factor (TNF), especially upon contact with pathogen-associated molecular patterns. Consequently, TNF not only acts as a macrophage-derived effector molecule but also regulates the activity and viability of macr...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5059883/ https://ncbi.nlm.nih.gov/pubmed/27899821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.285 |
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