MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors

MicroRNAs (miRNAs) are key regulators of hematopoietic cell differentiation and may contribute to altered growth of leukemic stem cells. Using microarray-based miRNA profiling, we found that miRNA 486 (miR-486) is significantly upregulated in chronic myeloid leukemia (CML) compared with normal CD34(...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Wang, Li-Sheng, Li, Ling, Li, Liang, Chu, Su, Shiang, Keh-Dong, Li, Min, Sun, Hui-Yan, Xu, Jun, Xiao, Feng-Jun, Sun, Guihua, Rossi, John J., Ho, YinWei, Bhatia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335083/
https://ncbi.nlm.nih.gov/pubmed/25515961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-581926
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