MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors

MicroRNAs (miRNAs) are key regulators of hematopoietic cell differentiation and may contribute to altered growth of leukemic stem cells. Using microarray-based miRNA profiling, we found that miRNA 486 (miR-486) is significantly upregulated in chronic myeloid leukemia (CML) compared with normal CD34(...

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Bibliographic Details
Published in:Blood
Main Authors: Wang, Li-Sheng, Li, Ling, Li, Liang, Chu, Su, Shiang, Keh-Dong, Li, Min, Sun, Hui-Yan, Xu, Jun, Xiao, Feng-Jun, Sun, Guihua, Rossi, John J., Ho, YinWei, Bhatia, Ravi
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2015
Subjects:
Myeloid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335083/
https://ncbi.nlm.nih.gov/pubmed/25515961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-581926
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