MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors

MicroRNAs (miRNAs) are key regulators of hematopoietic cell differentiation and may contribute to altered growth of leukemic stem cells. Using microarray-based miRNA profiling, we found that miRNA 486 (miR-486) is significantly upregulated in chronic myeloid leukemia (CML) compared with normal CD34(...

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Udgivet i:Blood
Main Authors: Wang, Li-Sheng, Li, Ling, Li, Liang, Chu, Su, Shiang, Keh-Dong, Li, Min, Sun, Hui-Yan, Xu, Jun, Xiao, Feng-Jun, Sun, Guihua, Rossi, John J., Ho, YinWei, Bhatia, Ravi
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2015
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335083/
https://ncbi.nlm.nih.gov/pubmed/25515961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-581926
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