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Structurally Similar Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors Exhibit Five Distinct Pharmacological Effects

Activation of nicotinic acetylcholine receptors (nAChRs) is associated with the binding of agonists such as acetylcholine to an extracellular site that is located at the interface between two adjacent receptor subunits. More recently, there has been considerable interest in compounds, such as positi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gill-Thind, JasKiran K., Dhankher, Persis, D'Oyley, Jarryl M., Sheppard, Tom D., Millar, Neil S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319022/
https://ncbi.nlm.nih.gov/pubmed/25516597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619221
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