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Contrasting Properties of α7-Selective Orthosteric and Allosteric Agonists Examined on Native Nicotinic Acetylcholine Receptors

Subtype-selective ligands are important tools for the pharmacological characterisation of neurotransmitter receptors. This is particularly the case for nicotinic acetylcholine receptors (nAChRs), given the heterogeneity of their subunit composition. In addition to agonists and antagonists that inter...

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Detalhes bibliográficos
Main Authors: Gill, JasKiran K., Chatzidaki, Anna, Ursu, Daniel, Sher, Emanuele, Millar, Neil S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558472/
https://ncbi.nlm.nih.gov/pubmed/23383051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055047
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