Contrasting Properties of α7-Selective Orthosteric and Allosteric Agonists Examined on Native Nicotinic Acetylcholine Receptors

Subtype-selective ligands are important tools for the pharmacological characterisation of neurotransmitter receptors. This is particularly the case for nicotinic acetylcholine receptors (nAChRs), given the heterogeneity of their subunit composition. In addition to agonists and antagonists that inter...

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Bibliographic Details
Main Authors: Gill, JasKiran K., Chatzidaki, Anna, Ursu, Daniel, Sher, Emanuele, Millar, Neil S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558472/
https://ncbi.nlm.nih.gov/pubmed/23383051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055047
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