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Structurally Similar Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors Exhibit Five Distinct Pharmacological Effects

Activation of nicotinic acetylcholine receptors (nAChRs) is associated with the binding of agonists such as acetylcholine to an extracellular site that is located at the interface between two adjacent receptor subunits. More recently, there has been considerable interest in compounds, such as positi...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Gill-Thind, JasKiran K., Dhankher, Persis, D'Oyley, Jarryl M., Sheppard, Tom D., Millar, Neil S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319022/
https://ncbi.nlm.nih.gov/pubmed/25516597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619221
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