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Differential Contribution of Subunit Interfaces to α9α10 Nicotinic Acetylcholine Receptor Function

Nicotinic acetylcholine receptors can be assembled from either homomeric or heteromeric pentameric subunit combinations. At the interface of the extracellular domains of adjacent subunits lies the acetylcholine binding site, composed of a principal component provided by one subunit and a complementa...

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Publicat a:Mol Pharmacol
Autors principals: Boffi, Juan Carlos, Marcovich, Irina, Gill-Thind, JasKiran K., Corradi, Jeremías, Collins, Toby, Lipovsek, María Marcela, Moglie, Marcelo, Plazas, Paola V., Craig, Patricio O., Millar, Neil S., Bouzat, Cecilia, Elgoyhen, Ana Belén
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325082/
https://ncbi.nlm.nih.gov/pubmed/28069778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.107482
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