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Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Positive allosteric modulators of α7 nicotinic acetylcholine receptors (nAChRs) have attracted considerable interest as potential tools for the treatment of neurological and psychiatric disorders such as Alzheimer's disease and schizophrenia. However, despite the potential therapeutic usefulnes...

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Detalhes bibliográficos
Main Authors: Young, Gareth T., Zwart, Ruud, Walker, Alison S., Sher, Emanuele, Millar, Neil S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535569/
https://ncbi.nlm.nih.gov/pubmed/18791069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804372105
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