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Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies

Neuronal insulin signaling abnormalities have been associated with Alzheimer's disease (AD). However, the specificity of this association and its underlying mechanisms have been unclear. This study investigated the expression of abnormal serine phosphorylation of insulin receptor substrate 1 (I...

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Bibliografski detalji
Izdano u:Acta Neuropathol
Glavni autori: Yarchoan, Mark, Toledo, Jon B., Lee, Edward B., Arvanitakis, Zoe, Kazi, Hala, Han, Li-Ying, Louneva, Natalia, Lee, Virginia M.-Y., Kim, Sangwon F., Trojanowski, John Q., Arnold, Steven E.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304658/
https://ncbi.nlm.nih.gov/pubmed/25107476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1328-5
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