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Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies

Neuronal insulin signaling abnormalities have been associated with Alzheimer's disease (AD). However, the specificity of this association and its underlying mechanisms have been unclear. This study investigated the expression of abnormal serine phosphorylation of insulin receptor substrate 1 (I...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Acta Neuropathol
Κύριοι συγγραφείς: Yarchoan, Mark, Toledo, Jon B., Lee, Edward B., Arvanitakis, Zoe, Kazi, Hala, Han, Li-Ying, Louneva, Natalia, Lee, Virginia M.-Y., Kim, Sangwon F., Trojanowski, John Q., Arnold, Steven E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304658/
https://ncbi.nlm.nih.gov/pubmed/25107476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1328-5
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