Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies

Neuronal insulin signaling abnormalities have been associated with Alzheimer's disease (AD). However, the specificity of this association and its underlying mechanisms have been unclear. This study investigated the expression of abnormal serine phosphorylation of insulin receptor substrate 1 (I...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol
Huvudupphovsmän: Yarchoan, Mark, Toledo, Jon B., Lee, Edward B., Arvanitakis, Zoe, Kazi, Hala, Han, Li-Ying, Louneva, Natalia, Lee, Virginia M.-Y., Kim, Sangwon F., Trojanowski, John Q., Arnold, Steven E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304658/
https://ncbi.nlm.nih.gov/pubmed/25107476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1328-5
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