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Tau-Directed Drug Discovery for Alzheimer’s Disease and Related Tauopathies: A Focus on Tau Assembly Inhibitors
The microtubule-associated protein tau forms insoluble filaments that deposit as neurofibrillary tangles (NFTs) in the brains of those with Alzheimer’s disease (AD) and other related neurodegenerative disorders. The presence of both NFTs and amyloid β (Aβ)-containing senile plaques within the brain...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864354/ https://ncbi.nlm.nih.gov/pubmed/19744482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.08.031 |
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