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Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies

Neuronal insulin signaling abnormalities have been associated with Alzheimer's disease (AD). However, the specificity of this association and its underlying mechanisms have been unclear. This study investigated the expression of abnormal serine phosphorylation of insulin receptor substrate 1 (I...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Yarchoan, Mark, Toledo, Jon B., Lee, Edward B., Arvanitakis, Zoe, Kazi, Hala, Han, Li-Ying, Louneva, Natalia, Lee, Virginia M.-Y., Kim, Sangwon F., Trojanowski, John Q., Arnold, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304658/
https://ncbi.nlm.nih.gov/pubmed/25107476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1328-5
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