Initial Testing (Stage 1) of the mTOR Kinase Inhibitor AZD8055 by the Pediatric Preclinical Testing Program

BACKGROUND: AZD8055 is a small molecule ATP-competitive inhibitor of the serine/threonine kinase mTOR that regulates cap-dependent translation through the mTORC1 complex and Akt activation through the mTORC2 complex. PROCEDURES: AZD8055 was tested against the PPTP in vitro panel at concentrations ra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Houghton, Peter J., Gorlick, Richard, Kolb, E. Anders, Lock, Richard, Carol, Hernan, Morton, Christopher L., Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Phelps, Doris, Maris, John M., Billups, Catherine, Smith, Malcolm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304209/
https://ncbi.nlm.nih.gov/pubmed/21337679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22935
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados