Reactive γ-Ketoaldehydes Promote Protein Misfolding and Preamyloid Oligomer Formation in Rapidly-Activated Atrial Cells

Rapid activation causes remodeling of atrial myocytes resembling that which occurs in experimental and human atrial fibrillation (AF). Using this cellular model, we previously observed transcriptional upregulation of proteins implicated in protein misfolding and amyloidosis. For organ-specific amylo...

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Detaylı Bibliyografya
Yayımlandı:J Mol Cell Cardiol
Asıl Yazarlar: Sidorova, Tatiana N., Yermalitskaya, Liudmila V., Mace, Lisa C., Wells, K. Sam, Boutaud, Olivier, Prinsen, Joseph K., Davies, Sean S., Roberts, L. Jackson, Dikalov, Sergey I., Glabe, Charles G., Amarnath, Venkataraman, Barnett, Joey V., Murray, Katherine T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302000/
https://ncbi.nlm.nih.gov/pubmed/25463275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.11.013
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