Reactive γ-Ketoaldehydes Promote Protein Misfolding and Preamyloid Oligomer Formation in Rapidly-Activated Atrial Cells

Rapid activation causes remodeling of atrial myocytes resembling that which occurs in experimental and human atrial fibrillation (AF). Using this cellular model, we previously observed transcriptional upregulation of proteins implicated in protein misfolding and amyloidosis. For organ-specific amylo...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Mol Cell Cardiol
Κύριοι συγγραφείς: Sidorova, Tatiana N., Yermalitskaya, Liudmila V., Mace, Lisa C., Wells, K. Sam, Boutaud, Olivier, Prinsen, Joseph K., Davies, Sean S., Roberts, L. Jackson, Dikalov, Sergey I., Glabe, Charles G., Amarnath, Venkataraman, Barnett, Joey V., Murray, Katherine T.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302000/
https://ncbi.nlm.nih.gov/pubmed/25463275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.11.013
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