Hypertension Is Associated With Preamyloid Oligomers in Human Atrium: A Missing Link in Atrial Pathophysiology?

BACKGROUND: Increasing evidence indicates that proteotoxicity plays a pathophysiologic role in experimental and human cardiomyopathy. In organ‐specific amyloidoses, soluble protein oligomers are the primary cytotoxic species in the process of protein aggregation. While isolated atrial amyloidosis ca...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Sidorova, Tatiana N., Mace, Lisa C., Wells, K. Sam, Yermalitskaya, Liudmila V., Su, Pei‐Fang, Shyr, Yu, Atkinson, James B., Fogo, Agnes B., Prinsen, Joseph K., Byrne, John G., Petracek, Michael R., Greelish, James P., Hoff, Steven J., Ball, Stephen K., Glabe, Charles G., Brown, Nancy J., Barnett, Joey V., Murray, Katherine T.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338732/
https://ncbi.nlm.nih.gov/pubmed/25468655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001384
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