Hypertension Is Associated With Preamyloid Oligomers in Human Atrium: A Missing Link in Atrial Pathophysiology?

BACKGROUND: Increasing evidence indicates that proteotoxicity plays a pathophysiologic role in experimental and human cardiomyopathy. In organ‐specific amyloidoses, soluble protein oligomers are the primary cytotoxic species in the process of protein aggregation. While isolated atrial amyloidosis ca...

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Библиографические подробности
Опубликовано в: :J Am Heart Assoc
Главные авторы: Sidorova, Tatiana N., Mace, Lisa C., Wells, K. Sam, Yermalitskaya, Liudmila V., Su, Pei‐Fang, Shyr, Yu, Atkinson, James B., Fogo, Agnes B., Prinsen, Joseph K., Byrne, John G., Petracek, Michael R., Greelish, James P., Hoff, Steven J., Ball, Stephen K., Glabe, Charles G., Brown, Nancy J., Barnett, Joey V., Murray, Katherine T.
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2014
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338732/
https://ncbi.nlm.nih.gov/pubmed/25468655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001384
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