Hypertension Is Associated With Preamyloid Oligomers in Human Atrium: A Missing Link in Atrial Pathophysiology?

BACKGROUND: Increasing evidence indicates that proteotoxicity plays a pathophysiologic role in experimental and human cardiomyopathy. In organ‐specific amyloidoses, soluble protein oligomers are the primary cytotoxic species in the process of protein aggregation. While isolated atrial amyloidosis ca...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Sidorova, Tatiana N., Mace, Lisa C., Wells, K. Sam, Yermalitskaya, Liudmila V., Su, Pei‐Fang, Shyr, Yu, Atkinson, James B., Fogo, Agnes B., Prinsen, Joseph K., Byrne, John G., Petracek, Michael R., Greelish, James P., Hoff, Steven J., Ball, Stephen K., Glabe, Charles G., Brown, Nancy J., Barnett, Joey V., Murray, Katherine T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338732/
https://ncbi.nlm.nih.gov/pubmed/25468655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001384
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi