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Characterization of scavengers of γ-ketoaldehydes that do not inhibit prostaglandin biosynthesis
Expression of cyclooxygenase-2 (COX-2) is associated with the development of many pathologic conditions. The product of COX-2, prostaglandin H(2) (PGH(2)) can spontaneously rearrange to form reactive γ-ketoaldehydes called levuglandins (LGs). This γ-ketoaldehyde structure confers a high degree of re...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831641/ https://ncbi.nlm.nih.gov/pubmed/20041722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900407a |
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