Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs

The insulin receptor (IR) regulates nutrient uptake and utilization in multiple organs, but its role in the intestinal epithelium is not defined. This study developed a mouse model with villin-Cre (VC) recombinase-mediated intestinal epithelial cell (IEC)-specific IR deletion (VC-IR(Δ/Δ)) and litter...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Andres, Sarah F., Santoro, M. Agostina, Mah, Amanda T., Keku, J. Adeola, Bortvedt, Amy E., Blue, R. Eric, Lund, P. Kay
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Hormones and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297856/
https://ncbi.nlm.nih.gov/pubmed/25394660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00287.2014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados