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Intestinal Neurod1 expression impairs paneth cell differentiation and promotes enteroendocrine lineage specification

Transcription factor Neurod1 is required for enteroendocrine progenitor differentiation and maturation. Several earlier studies indicated that ectopic expression of Neurod1 converted non- neuronal cells into neurons. However, the functional consequence of ectopic Neurod1 expression has not been exam...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Hui Joyce, Ray, Subir K., Pan, Ning, Haigh, Jody, Fritzsch, Bernd, Leiter, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925293/
https://ncbi.nlm.nih.gov/pubmed/31862906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55292-7
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