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Reduced insulin-like growth factor 1 receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk

BACKGROUND: Hyperinsulinemia resulting from obesity and insulin resistance is associated with increased risk of many cancers, but the biology underlying this risk is unclear. We hypothesized that increased mRNA levels of the insulin-like growth factor 1 receptor (IGF1R) versus the insulin receptor (...

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Detaylı Bibliyografya
Asıl Yazarlar: Santoro, M. Agostina, Andres, Sarah F., Galanko, Joseph A., Sandler, Robert S., Keku, Temitope O., Lund, P. Kay
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201381/
https://ncbi.nlm.nih.gov/pubmed/25017244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-14-0177
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