Insulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: evidence that IR-B limits proliferation

Por Andres, Sarah F., Simmons, James G., Mah, Amanda T., Santoro, M. Agostina, Van Landeghem, Laurianne, Lund, P. Kay
Publicado em 2013

Reduced insulin-like growth factor 1 receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk

Por Santoro, M. Agostina, Andres, Sarah F., Galanko, Joseph A., Sandler, Robert S., Keku, Temitope O., Lund, P. Kay
Publicado em 2014

Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon

Por Santoro, M. Agostina, Blue, R. Eric, Andres, Sarah F., Mah, Amanda T., Van Landeghem, Laurianne, Lund, P. Kay
Publicado no Am J Physiol Gastrointest Liver Physiol (2015)

Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells

Por Moorefield, Emily C., Andres, Sarah F., Blue, R. Eric, Van Landeghem, Laurianne, Mah, Amanda T., Santoro, M. Agostina, Ding, Shengli
Publicado no Aging (Albany NY) (2017)

Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs

Por Andres, Sarah F., Santoro, M. Agostina, Mah, Amanda T., Keku, J. Adeola, Bortvedt, Amy E., Blue, R. Eric, Lund, P. Kay
Publicado no Am J Physiol Gastrointest Liver Physiol (2014)

IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations

Por Van Landeghem, Laurianne, Santoro, M. Agostina, Mah, Amanda T., Krebs, Adrienne E., Dehmer, Jeffrey J., McNaughton, Kirk K., Helmrath, Michael A., Magness, Scott T., Lund, P. Kay
Publicado no FASEB J (2015)

Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation

Por Van Landeghem, Laurianne, Santoro, M. Agostina, Krebs, Adrienne E., Mah, Amanda T., Dehmer, Jeffrey J., Gracz, Adam D., Scull, Brooks P., McNaughton, Kirk, Magness, Scott T., Lund, P. Kay
Publicado em 2012