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Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon
Current views suggest that apoptosis eliminates genetically damaged cells that may otherwise form tumors. Prior human studies link elevated insulin and reduced apoptosis to risk of colorectal adenomas. We hypothesized that hyperinsulinemia associated with obesity would lead to reduced colon epitheli...
में बचाया:
| में प्रकाशित: | Am J Physiol Gastrointest Liver Physiol |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Physiological Society
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593818/ https://ncbi.nlm.nih.gov/pubmed/26251471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00189.2015 |
| टैग : |
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