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Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells
Intestinal epithelial stem cells (IESCs) are critical to maintain intestinal epithelial function and homeostasis. We tested the hypothesis that aging promotes IESC dysfunction using old (18-22 months) and young (2-4 month) Sox9-EGFP IESC reporter mice. Different levels of Sox9-EGFP permit analyses o...
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| Veröffentlicht in: | Aging (Albany NY) |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5611984/ https://ncbi.nlm.nih.gov/pubmed/28854151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101279 |
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