Type-1-cytokines synergize with oncogene inhibition to induce tumor growth arrest

Both targeted inhibition of oncogenic driver mutations and immune-based therapies show efficacy in treatment of patients with metastatic cancer but responses can be either short-lived or incompletely effective. Oncogene inhibition can augment the efficacy of immune-based therapy but mechanisms by wh...

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Publicado no:Cancer Immunol Res
Main Authors: Acquavella, Nicolas, Clever, David, Yu, Zhiya, Roelke-Parker, Melody, Palmer, Douglas C., Xi, Liqiang, Pflicke, Holger, Ji, Yun, Gros, Alena, Hanada, Ken-ichi, Goldlust, Ian S., Mehta, Gautam U., Klebanoff, Christopher A., Crompton, Joseph G., Sukumar, Madhusudhanan, Morrow, James J., Franco, Zulmarie, Gattinoni, Luca, Liu, Hui, Wang, Ena, Marincola, Francesco, Stroncek, David F., Lee, Chyi-Chia R., Raffeld, Mark, Bosenberg, Marcus W., Roychoudhuri, Rahul, Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289107/
https://ncbi.nlm.nih.gov/pubmed/25358764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0122
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