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T cell receptor-ligand interactions: A conformational preequilibrium or an induced fit
Kinetic parameters of T cell receptor (TCR) interactions with its ligand have been proposed to control T cell activation. Analysis of kinetic data obtained has so far produced conflicting insights; here, we offer a consideration of this problem. As a model system, association and dissociation of a s...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC428473/ https://ncbi.nlm.nih.gov/pubmed/15178754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402840101 |
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