CD8 Kinetically Promotes Ligand Binding to the T-Cell Antigen Receptor

The mechanism of CD8 cooperation with the TCR in antigen recognition was studied on live T cells. Fluorescence correlation measurements yielded evidence of the presence of two TCR and CD8 subpopulations with different lateral diffusion rate constants. Independently, evidence for two subpopulations w...

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Hauptverfasser: Gakamsky, Dmitry M., Luescher, Immanuel F., Pramanik, Aladdin, Kopito, Ronen B., Lemonnier, François, Vogel, Horst, Rigler, Rudolf, Pecht, Israel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2005
Schlagworte:
Cell Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366714/
https://ncbi.nlm.nih.gov/pubmed/15980174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.061671
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