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Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptor
Thermodynamics and kinetics of the interaction between T cell receptor specific for cytomegalovirus peptide (TCR(CMV)) and its specific ligand, pp65–HLA-A*0201 complex, were studied by surface plasmon resonance and stopped-flow methods. In the latter measurements, fluorescence resonance energy trans...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2034217/ https://ncbi.nlm.nih.gov/pubmed/17921250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707061104 |
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