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T cell receptor-ligand interactions: A conformational preequilibrium or an induced fit

Kinetic parameters of T cell receptor (TCR) interactions with its ligand have been proposed to control T cell activation. Analysis of kinetic data obtained has so far produced conflicting insights; here, we offer a consideration of this problem. As a model system, association and dissociation of a s...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Gakamsky, Dmitry M., Luescher, Immanuel F., Pecht, Israel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC428473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15178754/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402840101
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