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Ligand Binding to the Androgen Receptor Induces Conformational Changes That Regulate Phosphatase Interactions

We describe a mechanism for protein phosphatase 2A (PP2A) targeting to the androgen receptor (AR) and provide insight into the more general issue of kinase and phosphatase interactions with AR. Simian virus 40 (SV40) small t antigen (ST) binding to N-terminal HEAT repeats in the PP2A A subunit induc...

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Hlavní autoři: Yang, Chun-Song, Xin, Hong-Wu, Kelley, Joshua B., Spencer, Adam, Brautigan, David L., Paschal, Bryce M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899975/
https://ncbi.nlm.nih.gov/pubmed/17325038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02411-06
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