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A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.

Protein tyrosine phosphatases (PTPases) play critical roles in the intracellular signal transduction pathways that regulate cell transformation, growth, and proliferation. The structures of several different PTPases have revealed a conserved active site architecture in which a phosphate-binding loop...

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Autori principali: Schubert, H. L., Fauman, E. B., Stuckey, J. A., Dixon, J. E., Saper, M. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143214/
https://ncbi.nlm.nih.gov/pubmed/8528087
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