Lataa...
Pramipexole Derivatives as Potent and Selective Dopamine D(3) Receptor Agonists with Improved Human Microsomal Stability
We report herein the synthesis and evaluation of a series of new pramipexole derivatives as highly potent and selective dopamine-3 (D(3)) receptor agonists. A number of these new compounds bind to the D(3) receptor with subnanomolar affinities and show excellent selectivity (>10,000) for the D(3)...
Tallennettuna:
| Julkaisussa: | ChemMedChem |
|---|---|
| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277207/ https://ncbi.nlm.nih.gov/pubmed/25338762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201402398 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|