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CJ-1639: A Potent and Highly Selective Dopamine D3 Receptor Full Agonist
[Image: see text] We have identified several ligands with high binding affinities to the dopamine D3 receptor and excellent selectivity over the D2 and D1 receptors. CJ-1639 (17) binds to the D3 receptor with a K(i) value of 0.50 nM and displays a selectivity of >5000 times over D2 and D1 recepto...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3224040/ https://ncbi.nlm.nih.gov/pubmed/22125662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200100t |
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