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High-affinity and selective dopamine D(3) receptor full agonists
We have designed, synthesized and evaluated a series of new compounds with the goal to identify potent and selective D(3) ligands. The two most potent and selective new D(3) ligands are compounds 38 and 52, which bind to the D(3) receptors with a K(i) value of <1 nM and display a selectivity of 4...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461280/ https://ncbi.nlm.nih.gov/pubmed/22871578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.07.003 |
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