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Impact of copula directional specification on multi-trial evaluation of surrogate endpoints
Evaluation of surrogate endpoints using patient-level data from multiple trials is the gold standard, where multi-trial copula models are used to quantify both patient-level and trial-level surrogacy. While limited consideration has been given in the literature to copula choice (e.g., Clayton), no p...
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Publicado en: | J Biopharm Stat |
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Autores principales: | , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270950/ https://ncbi.nlm.nih.gov/pubmed/24905465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2014.920870 |
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