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Biomarkers and Surrogate Endpoints In Clinical Trials

One of the most important considerations in designing clinical trials is the choice of outcome measures. These outcome measures could be clinically meaningful endpoints that are direct measures of how patients feel, function and survive. Alternatively, indirect measures, such as biomarkers that incl...

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Библиографические подробности
Главные авторы: Fleming, Thomas R., Powers, John H
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551627/
https://ncbi.nlm.nih.gov/pubmed/22711298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5403
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