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Biomarkers and Surrogate Endpoints In Clinical Trials

One of the most important considerations in designing clinical trials is the choice of outcome measures. These outcome measures could be clinically meaningful endpoints that are direct measures of how patients feel, function and survive. Alternatively, indirect measures, such as biomarkers that incl...

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Autori principali: Fleming, Thomas R., Powers, John H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551627/
https://ncbi.nlm.nih.gov/pubmed/22711298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5403
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