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Bayesian Adaptive Trial Design for a Newly Validated Surrogate Endpoint
The evaluation of surrogate endpoints for primary use in future clinical trials is an increasingly important research area, due to demands for more efficient trials coupled with recent regulatory acceptance of some surrogates as ‘valid.’ However, little consideration has been given to how a trial wh...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218207/ https://ncbi.nlm.nih.gov/pubmed/21838811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2011.01647.x |
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