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Center-Within-Trial Versus Trial-Level Evaluation of Surrogate Endpoints

Evaluation of candidate surrogate endpoints using individual patient data from multiple clinical trials is considered the gold standard approach to validate surrogates at both patient and trial levels. However, this approach assumes the availability of patient-level data from a relatively large coll...

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Bibliografiska uppgifter
Huvudupphovsmän: Renfro, Lindsay A., Shi, Qian, Xue, Yuan, Li, Junlong, Shang, Hongwei, Sargent, Daniel J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104720/
https://ncbi.nlm.nih.gov/pubmed/25061255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2014.03.011
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