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Center-Within-Trial Versus Trial-Level Evaluation of Surrogate Endpoints
Evaluation of candidate surrogate endpoints using individual patient data from multiple clinical trials is considered the gold standard approach to validate surrogates at both patient and trial levels. However, this approach assumes the availability of patient-level data from a relatively large coll...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104720/ https://ncbi.nlm.nih.gov/pubmed/25061255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2014.03.011 |
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