Massively parallel determination and modeling of endonuclease substrate specificity

We describe the identification and characterization of novel homing endonucleases using genome database mining to identify putative target sites, followed by high throughput activity screening in a bacterial selection system. We characterized the substrate specificity and kinetics of these endonucle...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Thyme, Summer B., Song, Yifan, Brunette, T. J., Szeto, Mindy D., Kusak, Lara, Bradley, Philip, Baker, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Nucleic Acid Enzymes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267613/
https://ncbi.nlm.nih.gov/pubmed/25389263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1096
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk