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Mining Endonuclease Cleavage Determinants in Genomic Sequence Data

Homing endonucleases have great potential as tools for targeted gene therapy and gene correction, but identifying variants of these enzymes capable of cleaving specific DNA targets of interest is necessary before the widespread use of such technologies is possible. We identified homologues of the LA...

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Bibliografische gegevens
Hoofdauteurs: Szeto, Mindy D., Boissel, Sandrine J. S., Baker, David, Thyme, Summer B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173205/
https://ncbi.nlm.nih.gov/pubmed/21778233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259572
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