Identification of Small Molecule Inhibitors of Pre-mRNA Splicing

Eukaryotic pre-mRNA splicing is an essential step in gene expression for all genes that contain introns. In contrast to transcription and translation, few well characterized chemical inhibitors are available with which to dissect the splicing process, particularly in cells. Therefore, the identifica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Pawellek, Andrea, McElroy, Stuart, Samatov, Timur, Mitchell, Lee, Woodland, Andrew, Ryder, Ursula, Gray, David, Lührmann, Reinhard, Lamond, Angus I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
RNA
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263873/
https://ncbi.nlm.nih.gov/pubmed/25281741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.590976
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