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SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing
Pre-mRNA splicing is catalyzed by the spliceosome, a multi-megadalton ribonucleoprotein machine. Previous work from our laboratory revealed the splicing factor SRSF1 as a regulator of the SUMO pathway, leading us to explore a connection between this pathway and the splicing machinery. We show here t...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499870/ https://ncbi.nlm.nih.gov/pubmed/28379520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx213 |
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