Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle

Akt/PKB is a key signaling molecule in higher eukaryotes and a crucial protein kinase in human health and disease. Phosphorylation, acetylation, and ubiquitylation have been reported as important regulatory post-translational modifications of this kinase. We describe here that Akt is modified by SUM...

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Главные авторы: Risso, Guillermo, Pelisch, Federico, Pozzi, Berta, Mammi, Pablo, Blaustein, Matías, Colman-Lerner, Alejandro, Srebrow, Anabella
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865012/
https://ncbi.nlm.nih.gov/pubmed/24013425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26183
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